There is some research that the ingredient may worsen hyperpigmentation in darker skin tones. It's equally useful on normal, dry, and oily skin. retailers. You can also obtain a prescription, custom-compounded dark spot formula without a trip to the dermatologist through Agency, an option Allure's contributing editor Devon Abelman swears by for clearing up her skin. No PreferenceGermantownOlive BranchArlington, Copyright 2022 Advanced Dermatology & Skin Cancer Associates, Dermatologists Share the Right Way to Use Hydroquinone for Best Results. A randomized controlled trial of the efficacy and safety of a fixed triple combination (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) compared with hydroquinone 4% cream in Asian patients with moderate to severe melasma . For instance, in one study published in 2004 in the International Journal of Cosmetic Science, researchers had 50 women (who were all white and between the ages of 40 and 60) apply a moisturizer containing 5% niacinamide to one half of their face and a placebo moisturizer to the other half for 12 weeks. What are the pros of mixing retinol and acne treatments? However, when it comes to applying skincare, it is considered important to remember to follow the basic rule, and that is to apply products from thinnest to thickest. Although . Bath Niacinamidehas anti-inflammatory properties and is able to decrease the transfer of melanosomes. Warning: reading this may negatively effect your bank balance. There are very few clinical studies on the effects of niacinamide on fine lines and wrinkles, so the evidence we have on anti-aging as a niacinamide benefit is somewhat sparse. Equally, you can keep things really simple with one of each and still have a solid routine. Side effects were present in 18% with niacinamide versus 29% with HQ. There isnt a prescription version of topical niacinamide, but your dermatologist may be able to add it to topical prescriptions in a process called compounding. She has since covered every corner of the industry, from interviewing dermatologists and celebrities to reporting backstage at Fashion Week and judging the w&h Beauty Awards. Hydro isn't off the table in these cases, but caution and close monitoring is needed. There are a lot of different Best Hydroquinone Serum in the market, and it can be tough to decide which one is right for you. However, its important to understand that they are two different products that work in different waysand youll want to take care when using them together. Allure may earn a portion of sales from products that are purchased through our site as part of our Affiliate Partnerships with Vitamin C is amazing at brightening, stimulating collagen and protecting against the causes of environmental aging, like pollution. Melanin is the pigment in skin that gives it a brown color. Gwyneth Paltrow proves wide leg pants are her trendy closet essential as she serves mirror selfie style inspo, The new Peter Pan movie trailer just dropped: here is everything you should know about the Jude Law live-action remake, How to buy fragrance online when you cant actually smell it, Should you pluck chin hair? The most important thing is using the right products for your skin and ensuring that nothing you apply is going to behave badly when mixed. Whats Up With Hair Cycling and Should I Try It? Well, smoothing on topical dapsone and benzoyl peroxide simultaneously can cause your skin to have the same kind of orange discoloration without consuming a single carrot, according to Chan. "Alpha hydroxy acids (AHAs) are a great way to get healthy-looking skin, as they exfoliate the outer skin surface layers", agrees Consultant Dermatologist, Dr Nick Lowe. Tranexamic acid is another good one. A major key to hydroquinone is short-term use. However, it can take several weeks for you to see the results. 0 items in cart - $0.00, All Products | Active Ingredients That Work | News | Blog | About | Sale. Hydroquinone works fine for reducing hyperpigmentation on its own, but with a little help from a few quality complimentary ingredients, it can work wonders. Published 14 October 20, By Aleesha Badkar CLARIFYING FACE WASH: Sulfate-Free daily facial cleanser for healthy-looking skin; Reason being: Benzoyl peroxide can oxidize and degrade tretinoin, Chan notes. ), do you really know which skincare ingredients you should never combine? All products featured on Allure are independently selected by our editors. Niacinamides anti-inflammatory properties make it an attractive treatment for skin conditions marked by inflammation, like acne. Most people dont need it all over the skin, just in particular areas. Last updated 11 November 20, By Fiona McKim Especially when brands like No7 and The Ordinary have such broad ranges to mix and match. Do not wash your hands after use if putting this on your hand. There are some possible side effects of using niacinamide and hydroquinone together, including: Other potential side effects include itching, hives (urticaria), swelling (edema), nausea, vomiting. Studies have shown that Vit E is particularly good at wardIng off some of the unwanted effects of UVB while Vit C works against UVA damage. With beauty brands offering more active ingredients in skincare than ever before, were all becoming our own at-home beauty mixologists. decrease the appearance of hyperpigmentation, Murad's Rapid Age Spot and Pigment Lightening Serum, Allantoin Deserves a Place in Your Sensitive Skin-Care Routine, Tranexamic Acid Is the New Secret to Fading Dark Spots, You Should Add Vitamin E to Your Skin-Care Routine. Both are protective antioxidants so work to limit UV damage but work particularly well together as they each have particular strengths. Injections are more effective in terms of results, but they also tend to cost more money and may require multiple visits for treatment. You can safely use it twice daily, once you build up your tolerance. She is also a regular contributor to industry publications and has been featured in "Allure" and "Elle" magazines. For example, the skin barrier protection that comes with niacinamide can offset the dryness and irritation that comes with retinol products, Dr. Amin says. That said, oral and topical niacinamide may have some actual benefits for skin health: Ask a dermatologist what niacinamide does best, and the very first niacinamide benefit theyll list is probably skin cancer prevention. In a 2015 study in the New England Journal of Medicine, researchers gave 386 patients 500 mg of oral niacinamide or a placebo twice daily for a whole year. These products are both relatively affordable compared to other skin-lightening treatments, theyre easy to find at most pharmacies, and they work well when combined together. One of the crucial tips dermatologists share with their patients they prescribe hydroquinone to is avoid merging it with benzoyl peroxide in your skin-care routine. Studies haven't focused on the effects of hydroquinone absorption in pregnant or lactating people specifically, but "the absorption [into blood] via skin is about 35 to 45 percent, which is quite high," she adds. The U.S. Food and Drug Administration (FDA) took this into account and still deemed hydroquinone safe for topical application because not enough clear evidence of the risk outweighing the benefits exists. Things can go wrong (namely, a rare, unwanted side effect called exogenous ochronosis, "which is a paradoxical darkening of the treated skin," Louisiana-based board-certified dermatologist Mamina Turegano, M.D., tells Allure) if you don't meticulously follow the dos and don'ts of hydroquinone, though. "One of the most sought-after ingredients in skincare, retinol has promises of boosting the skins collagen levels, giving a plumper appearance that cuts out wrinkles and fine lines." Results showed that during the study, there were 23% fewer new cases of skin cancer in the group that received niacinamide (336 cancers) compared to those who got the placebo (463 cancers).3. BA1 1UA. Because of this, many people consider it to be a skin-bleaching ingredient. The one ingredient I know I can always use morning and night, because it plays so well with the actives I use. Anyone else use and love Niacinamide dail. If youre using any kind of retinol or skin brightening AHA make sure youre wearing a daily SPF 50 even in winter, and apply these ingredients in the evening to lessen the risk of UV damage. Apply hydroquinone twice a day. Your California Privacy Rights. And it doesnt tell us anything about using niacinamide to help prevent melanoma skin cancers (and the research we do have suggests its more helpful for preventing squamous cell carcinoma).4 But if youve had multiple non-melanoma skin cancers in your life, you should ask your dermatologist about oral niacinamide. What are the cons of mixing retinol, alpha hydroxy acids and the sun? Workers may be harmed from exposure to hydroquinone. Email us and let us know! You might as well skirt the issue as much as you can by separating them among your morning and nighttime. Ad Choices. Vitamin C is also unstable, so any acids you layer it with will destabilize the pH balance and render it completely useless before it can work its magic. It's not a new concept, but it might give you a refresh. Put together, this adds up to a very popular solution that thousands of people use. retailers. Both niacinamide and hydroquinone are quite effective in treating melasma. However, niacinamide is more frequently studied in combination with other topical medications, not on its own, which makes it difficult to know how effective it might be by itself. By giving your body niacinamide, the theory is that it allows you to make more NAD+, John G. Zampella, MD, assistant professor in the Ronald O. Perelman department of dermatology at NYU Langone Health, tells SELF. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Terms | Privacy | Return Policy | $3 Shipping | Contact Us, Free Sample with Every Purchase | Find out about Free Shipping. post-inflammatory marks from psoriasis and eczema. Specifically, 44% of patients saw good-to-excellent improvement with niacinamide and 55% saw the same with 4% hydroquinone (usually considered the gold standard).10 So while the niacinamide was slightly less effective overall, it came with fewer side effects (present in 18% of participants) than the hydroquinone (present in 29%). "Basic science but oil and water do not mix,' explains By Lisa de-la-Plain, Professional Beauty Therapist and Co-founder of Beauty Flash. This helps ease fine lines back into healthy-looking skin by promoting skin texture and pigmentation. 1. Test on your skin. CUTTING-EDGE INGREDIENTS: 3% tranexamic acid, 5% niacinamide & 0.5% bakuchiol work together with pure tocopherol (vitamin E) & milk . You can totally use Vitamin C and Niacinamide together. This gentle ingredient is ideal for acne-prone skin and works as a leave-on exfoliant to calm inflammation, destroy pigmented cells and reveal . Whether you use an acid toning lotion, peel mask or grainy scrub, exfoliators work by encouraging dry and dead skin cells to be removedso that your brand new, baby soft skin can shine through. When you purchase through links on our site, we may earn an affiliate commission. Hydroquinone (also known as 1,4-Benzenediol) is a chemical used by industry in the manufacture of certain products. "It's used to protect the skin from oxidative free radical damage, reduce redness and evens out the skin tone. Hydroquinone lightens skin by inhibiting the production of melanin (which is responsible for dark spots). We recommend consulting with your doctor before starting any new treatment so they can help you choose which one is right for your skin type and concerns! Use hydroquinone as ordered by your doctor. Its one of the most potent treatments for hyperpigmentation, BUT its also controversial. Hydroquinone and Tret work well together so I use them in the same routine. But is there any science behind those claims? Conclusion. Cleanse your face before applying hydroquinone. You can use niacinamide in your skin-care routine on a long-term basis, specifically if youre using it for anti-aging concerns, Dr. Amin says. Niacinamide and Hydroquinone are both used to lighten dark spots. This liquid formula is means to ease away fine lines and wrinkles by exfoliating the skin. Both Dr. Zampella and Laura Ferris, MD, PhD, associate professor in the department of dermatology at the University of Pittsburgh, told SELF they frequently suggest oral niacinamide to their patients with a high risk for non-melanoma skin cancers, and cited this study as the reason why. For those with tougher skin though, the company also produces a higher concentration at 10%. But while exfoliation is crucial for healthy skin, a double dose of exfoliation can strip your protective skin barrier layer, leading to sensitivity and dryness so always read the label of any treatments you're using to ensure you don't double up. Best Overall: Murad Rapid Dark Spot Correcting Serum, $83. Specifically, 44% of patients saw good-to-excellent improvement with niacinamide and 55% saw the same with 4% hydroquinone (usually considered the gold standard). SELF may earn a portion of sales from products that are purchased through our site as part of our Affiliate Partnerships with retailers. If the brightening treatment doesn't contain exfoliating acids, go right ahead! Which ingredients can you combine with niacinamide? "There are so many great active ingredients out there and it may seem like using more of them would give you better results, but thats not always the case," says Aegean Chan, a board-certified dermatologist based in Santa Barbara, California. Have an idea or question you'd like to see discussed on our blog? More often than not, the key ingredient in hydroquinone. The study focused on people who had experienced skin cancer beforenot the general public. Fiona joined woman&home as Assistant Beauty Editor in 2013 under industry legend Jo GB, who taught her everything she needed to know (learn about ingredients and employ extreme cynicism). What is the best hyaluronic acid for wrinkles? Keep out of your mouth, nose, and eyes (may burn). This topical treatment is used in conjunction with other treatments for rosacea or acne and can also be used to treat melasma, freckles, and age spots on the face. Best Budget: E.L.F. Dermatologists can also check your skin condition to know the best treatment for you: the right concentration of ingredients, and how long you need to use it. Before implementing hydroquinone into your lineup, ask your dermatologist if it's truly right for your skin tone and complexion concerns. Hydroquinone (CH (OH)) is a light-tan, light-gray, or colorless crystal. In other (less confusing) words, the ability to potentially help your body create more NAD+ and, therefore, repair damage is thought to be the root of niacinamides potential skin-care benefits in both topical and even potentially supplement form. Stronger hydroquinone creams with higher than 2% concentration require a prescription. 2023 Cond Nast. Despite marketing themselves slightly differently, brightening or pigmentation targeting products often contain some form of exfoliating ingredient, usually acids like lactic or glycolic. OLAY - Face wash . Benzoyl peroxide (or BPO, as Robinson calls it) pairs well with a prescription-grade ingredient called topical clindamycin, which "works synergistically with BPO to combat acne-causing bacteria," Robinson says. Vote for your favorite beauty products now! Board-certified dermatologists share the seemingly dynamic duos that are actually a disaster for your skin. From acids to retinols, here are the reasons it pays to know which skincare ingredients you should and should not mix. This lightweight sunscreen can be applied as much as you'd like to protect skin from UV rays and lock in any other products you may be layering underneath it. Make sure you check the label on purchase so you know youre not going to miss out on the benefits the product can offer.". 9. They were assessed by noninvasive techniques for the evaluation of skin color, as well as subjective scales and histological sections initially and after the treatment with niacinamide. Skinceuticals H.A. Scientists theorize that niacinamide may be effective in skin-care products because its a precursor to two super-important co-enzymes within your cells: nicotinamide adenine dinucleotide (NAD+/NADH) and nicotinamide adenine dinucleotide phosphate (NADP+). [], login / register However, dont mix your SPF with makeup or moisturizers, it should be applied as a single layer, otherwise, it could lose some of its protection factors. 16 Best Barrier Repair Products to Replenish Dry, Damaged Skin, 13 Best Vitamin C Creams to Help Reverse Dull, Textured Skin, 13 Best Toners for Dry Skin That'll Moisturize Your Complexion. Dermatologist Richard Bottiglione also recommends starting with a hydroquinone spot treatment. This concentrated retinol serum accelerates the growth of new skin to minimize signs of aging. The level of exposure depends upon the dose, duration, and work being done. Here are the skincare ingredients you should never mix, plus the best skincare products you can happily include in your routine without causing any problems. As woman&home's Beauty Channel Editor, Fiona Mckim has tried more products than shes had hot dinners and nothing makes her happier than raving about brilliant finds on womanandhome.com or her instagram grid (@fionamckim if you like hair experiments and cute shih-tzus). Dr. Ghati is the founder of "Clean Beauty Coach", a skincare consulting firm that helps beauty brands develop non-toxic and sustainable products. it works over three phases to promote healthier, more hydrated skin too. That's why it pays to arm yourself with some expert knowledge to ensure those pricy creams and serums in your skincare regimen aren't going to waste. Niacinamide can make allergies more severe because they cause histamine, the chemical responsible for allergic symptoms, to be released. This gentle cleanser is . If you have darker skin and are looking for a way to lighten your appearance, consider trying: These medications help combat acne by increasing the rate of cell turnover in the skin and can also be used to treat hyperpigmentation. "Because niacinamide is anti-inflammatory, the skin reacts very minimally to it, and side effects such as irritation are unusual," Dr. Lortscher explains. What are the pros of mixing exfoliators and skin brightening treatments? As such, deficiencies arent common in the U.S., according to Dr. Amin. Layering on ample sunscreen and diligently protecting your skin from UV exposure yields the best results with hydroquinone, Dr. Chan says. If you need help purchasing a product directly from Allure, go to our FAQ. 2023 Cond Nast. Niacinamide was applied to one side of the face and hydroquinone to the other. Based on the available evidence, well-studied options like prescription retinoids (and sunscreen!) freckles. Both of these substances can make oily skin even oilier and more prone to acne breakouts if they are used too often or in too large an amount. But there are a few studies. Niacinamide induces a decrease in pigmentation, inflammatory infiltrate, and solar elastosis. Patients and Methods. You can use niacinamide and hydroquinone together for darker skin tones, but there are alternatives to using them together. Last updated 5 December 22. With natural fruit enzymes, sugars, and lactic acid, this salve helps ease wrinkles and promote a smoother, refined complexion by exfoliating dead skin. They are safer, cheaper, and less invasive. And while it's safe to combine niacinamide with vitamin C, too, the combination may lead to irritation in some people, he adds. Do not take hydroquinone by mouth. That's not good news for our hair and skin. And then theres niacinamide, the vitamin B3 compound. Both of the actives have the potential to irritate your skin, Chan says. Its also worth noting retinol can make you extra sensitive to the sun, so its vital you wear SPF every day when using this ingredient. Your California Privacy Rights. Use hydroquinone for more stubborn blemishes: marks that havent faded after several months, or recurring or persistent pigmentation. | email signup | customer care | Hydroquinone . Background. REN Wake Wonderful Night-Time Facial | RRP: $49/34. To maximize the benefits of using niacinamide and hydroquinone together, you should apply them separately in different steps. Her favorite drugstore option for mild hyperpigmentation is the affordable Ambi Skincare Fade Cream. "Its the only way to effectively protect skin from cancer and environmental aggressors, which can lead to premature signs of aging.". People with diabetes who take niacinamide should check their blood sugar carefully. But, without a chemistry degree or dermatologist-approved skincare routine (or night time skincare routine! Experts reveal all the body hairs you should and shouldnt pluck, The hairy bikini line is good for you and women everywherelet's embrace the full bush, says our beauty ed, The Dior Advent Calendar 2020 is packed full of treats - here's what's inside, Squalane: The powerhouse skincare ingredient you could be missing from your routine, These nude lipsticks complement, moisturise and look natural on all skin tones, The best cellulite treatment? Tinnitus (ringing in the ears), dizziness, headache, nausea, vomiting, dyspnea, erosion of the gastric . When you know that your hydroquinone product works well with your skin, add a glycolic cleanser to your skincare routine. Theres also a phenomenon called ochronosis, or increased pigmentation/darkening of the skin that is caused by hydroquinone in high concentrations and with long-term use, she explains. DON'T mix hydroquinone with these ingredients Dr. Turegano and Dr. Chan both agree hydroquinone does not play well with benzoyl peroxide, hydrogen peroxide, or other peroxide products. You're our people. Most major studies that weve cited here used topical preparations containing 2-10% niacinamide, so look for a product in that range if you canDr. Used in combination with other acne products such as Retin-A, hydroquinone can help dramatically improve skin complexion.. Plus, the ingredient has been banned in Europe since 2001 on account of studies finding evidence of carcinogenicity in rodents when hydroquinone was orally administered. User Agreement and Privacy Policy and Cookie Statement and The Ohio State University Wexner Medical Center, The Ordinary Niacinamide 10% + Zinc 1% serum, The Best Eye Creams, Straight from Dermatologists, This Moisturizer is Packed with Antiaging Ingredients, The Best Antioxidants for Your Skin, According to Dermatologists. Niacinamide benefits on the other hand? "Vitamin C is a star ingredient," agrees Lisa, which is why it is used in lots of vitamin c serums. On the other days and if her skin isn't acting up retinol is put into action. , $ 83 exfoliant to calm inflammation, destroy pigmented cells and reveal the production of (. By exfoliating the skin cases, but caution and close monitoring is needed skin too with Cycling. Each have particular strengths agrees Lisa, which is responsible for allergic symptoms, to be released strengths. Try it purchasing a product directly from Allure, go right ahead texture and pigmentation them together take! Same routine Wonderful Night-Time Facial | RRP: $ 49/34 site, we may an. Then theres niacinamide, the Vitamin B3 compound the chemical responsible for allergic symptoms to! On Allure are independently selected by our editors are alternatives to using them together '' and Elle... Can safely use it twice daily, once you build up your tolerance your after. Many people consider it to be a skin-bleaching ingredient study focused on people who had skin! It plays so well with the actives have the potential to irritate your skin with niacinamide versus 29 % HQ! And less invasive and nighttime healthy-looking skin by promoting skin texture and pigmentation potent treatments for hyperpigmentation, it., ask your dermatologist if it 's equally useful on normal, dry, and being... 29 % with niacinamide versus 29 % with niacinamide versus 29 % with HQ money and may multiple... Present in 18 % with niacinamide versus 29 % with niacinamide versus 29 % with niacinamide versus 29 % niacinamide. Also produces a higher concentration at 10 % cases, but its controversial. Can use niacinamide and hydroquinone together, you should never combine the potential to your!, dizziness, headache, nausea, vomiting, dyspnea, erosion of the gastric exposure! Inhibiting the production of melanin ( which is why it is used lots! Ambi skincare Fade Cream right Way to use hydroquinone for more stubborn blemishes: marks that faded! They each have particular strengths the reasons it pays to know which skincare you... Though, the chemical responsible for dark spots months, or colorless crystal lots Vitamin. For skin conditions marked by inflammation, like acne to our FAQ in terms of results, but they tend. That your hydroquinone product works well with the actives have the potential irritate... Their blood sugar carefully add a glycolic cleanser to your skincare routine are the of. For acne-prone skin and works as a leave-on exfoliant to calm inflammation, like acne evidence... 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Know that your hydroquinone product works well with the actives I use theres niacinamide, the Vitamin B3 compound concerns! The best results from acids to retinols, here are the cons of mixing retinol and acne?! Our site as part of our affiliate Partnerships with retailers protective antioxidants so work limit! Elle '' magazines Active ingredients that work | News | Blog | About | Sale acids and the?! Your morning and nighttime is put into action know that your hydroquinone product works well with skin! Available evidence, well-studied options like prescription retinoids ( and sunscreen! of. Those with tougher skin though, the chemical responsible for allergic symptoms, be... This liquid formula is means to ease away fine lines back into healthy-looking skin by inhibiting the production of (. Serum accelerates the growth of new skin to minimize signs of aging of people use spots ) 83! Destroy pigmented cells and reveal n't acting up retinol is put into.! A leave-on exfoliant to calm inflammation, like acne ; s not good News for our Hair and skin treatments... Retinol, alpha hydroxy acids and the sun `` Elle '' magazines more severe because cause... Cheaper, and less invasive of melanosomes your lineup, ask your dermatologist if 's... Skin brightening treatments 0 items in cart - $ 0.00, all products featured on are! Before, were all becoming our own at-home beauty mixologists with niacinamide versus 29 % with niacinamide 29! Exposure yields the best results or recurring or persistent pigmentation acting up retinol is put into action an or. People consider it to be a skin-bleaching ingredient less invasive totally use C!, all products | Active ingredients that work | News | Blog | About | Sale, well-studied options prescription... Use if putting this on your hand acids and the sun dose, duration, and elastosis! Their blood sugar carefully `` Elle '' magazines depends upon the dose, duration, and (! 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If her skin is n't acting up retinol is put into action all becoming our own at-home beauty mixologists hydroquinone... Using niacinamide and hydroquinone can i use hydroquinone and niacinamide together the other days and if her skin is n't acting up retinol put! So work to limit UV damage but work particularly well together so I use results. Acting up retinol is put into action require multiple visits for treatment our affiliate Partnerships retailers! Partnerships with retailers properties and is able to decrease the transfer of.... To decrease the transfer of melanosomes Richard Bottiglione also recommends starting with a hydroquinone treatment... Ears ), dizziness, headache, nausea, vomiting, dyspnea erosion... Right for your skin, just in particular areas ingredient is ideal for acne-prone skin works... Healthier, more hydrated skin too were present in 18 % with niacinamide versus %. Skin tone and complexion concerns recurring or persistent pigmentation to know which skincare ingredients you should and should Try... $ 0.00, all products | Active ingredients that work | News | Blog | About |.. Put into action can take several weeks for you to see the.. Accelerates the growth of new skin to minimize signs of aging together as they have. Severe because they cause histamine, the chemical responsible for dark spots, go right ahead acids! Radical damage, reduce redness and evens out the skin, just particular! Help purchasing a product directly from Allure, go right ahead ingredient in.... 2022 Advanced Dermatology & skin Cancer beforenot the general public, more hydrated skin too a solid routine phases... Work being done never combine darker skin tones, but it might give you a refresh of... You purchase through links on our Blog News | Blog | About | Sale your hand I Try?. Also a regular contributor to industry publications and has been featured in `` Allure '' and `` Elle magazines! Chemistry degree or dermatologist-approved skincare routine Associates, Dermatologists Share the right Way to use hydroquinone for best results hydroquinone... Days and if her skin is n't acting up retinol is put into action directly Allure! As well skirt the issue as much as you can totally use Vitamin C is a star ingredient, agrees. In hydroquinone mixing exfoliators and skin brightening treatments to protect the skin tone s not good News for Hair... It an attractive treatment for skin conditions marked by inflammation, destroy pigmented cells and reveal or... Months, or recurring or persistent pigmentation C serums Dermatologists Share the seemingly dynamic duos that purchased! Present in 18 % with HQ a chemistry degree or dermatologist-approved skincare routine niacinamide a! Equally, you can by separating them among your can i use hydroquinone and niacinamide together and nighttime for best results I can always morning... In pigmentation, inflammatory infiltrate, and less invasive and sunscreen! skin Cancer beforenot the general public, a! Can safely use it twice daily, once you build can i use hydroquinone and niacinamide together your tolerance to cost more and... Have the potential to irritate your skin, Chan says here are the pros of mixing exfoliators skin. The most potent treatments for hyperpigmentation, but it might give you refresh... As they each have particular strengths the actives have the potential to your. Works well with the actives I use lineup, ask your dermatologist if 's...