Finally knowing was a huge relief, she says. Patrick (Diego Velazquez) gets some encouragement from Mom. Their non-fiction counterparts were diagnosed at 15 months and 7 days old and received treatment at 5 and 4, respectively.[6]. Fate and determination push an idealistic father into joining forces with a reclusive medical researcher. Despite a timely topic and a pair of heavyweight leads, Extraordinary Measures never feels like much more than a made-for-TV tearjerker. [11] According to Roger Ebert's review, the character is based on Yuan-Tsong Chen,[6] a scientist and researcher from Duke University[12] who collaborated with Genzyme in producing Myozyme, the drug which received FDA approval. Good medical drama with an excellent performance by Harrison Ford - but could've have been much better Star Wars: Episode VI - Return of the Jedi (1983), Trailer Failure: Extraordinary Measures, Crazy on the Outside, and Bitch Slap. With children that young, the drama would have focused on the parents. Watch "It's a Very Exciting Time" from Extraordinary Measures, Watch "I Can Save Your Kids" from Extraordinary Measures. "It's been an incredible journey," says John, 42, a businessman from Princeton, N.J., played in the movie by Brendan Fraser. (Or alternately, that you cant see past the stereotyped version of your own bailiwick.) Dr. Robert Stonehill: I already work around the clock! It was the first film produced by CBS Films, the film division of CBS Corporation, who released the film on January 22, 2010. The small start-up company Priozyme was based on Oklahoma City-based Novazyme. Extraordinary Measures, based on events in the life of John Crowley and his family, dramatizes the father's quest to find a cure for Pompe disease, a relatively rare genetic condition that afflicts two of his three children. If they celebrated their 10th birthdays, it would be a miracle. Fate and determination push idealistic father, John Crowley (Brendan Fraser) into joining forces with reclusive medical researcher, Dr. Robert Stonehill (Harrison Ford). John recalls looking at Megan and telling her, "This means your heart is getting better. Watch "It's a Very Exciting Time" from Extraordinary Measures, Watch "I Can Save Your Kids" from Extraordinary Measures. Extraordinary Measures. This article is about a 2010 film. Also starring Golden Globe winner Kerri Russell, Extraordinary Measures is a true story of the power of love and faith against impossible odds. "I have a tiny little plaque on my desk which my mom gave me the week I started that tiny company. "People always say: 'How can you do it?' The larger company, called Zymagen in the film, was based on Genzyme in Cambridge, Massachusetts. Four other congregations with female pastors were also determined to be not in friendly cooperation with the SBC, as well as one removed over its abuse response. Also starring Golden Globe winner Kerri Russell, Extraordinary Measures is a true story of the power of love and faith against impossible odds. In Extraordinary Measures Brendan Fraser and Keri Russell play the parents of three children, two of whom suffer from Pompe disease, a genetic disorder which has them confined to wheelchairs and which will kill them in short order. Sitting in his wheelchair in the park one day, Patrick didn't even have the strength to throw bread to the ducks. [5], In the film, the children are 9 and 7 years old. The veteran actor brings to life another curmudgeonly character who, once his prickly exterior is stripped away, is. Though children are shown in peril at the hospital, there's nothing particularly graphic, and it might be a good launch point for discussing life-threatening disease with younger viewers. What is the life expectancy of a Pompe patient in real life. It was the first film produced by CBS Films, the film division of CBS Corporation, who released the film on January 22, 2010. Stars: Harrison Ford, Brendan Fraser, Keri. For information about Pompe disease, see: http://www.ninds.nih.gov/disorders/pompe/pompe.htm, http://genetics.emory.edu/docs/LSDC%20docs/Pompe%20dx.pdf. Extraordinary Measures: Directed by Tom Vaughan. : In consultation with pharmaceutical and academic researchers specializing in biomarkers, imaging, and trial-readiness, we design and implement projects through commercial research companies and academic labs to, : Scores of volunteers across North America have stepped up to lead, We have approved almost $2 million this yea, educated, empowered, and engaged community, Extraordinary Measures Updating the standard of care for FSHD, Extraordinary Measures Understanding the socioeconomic impact of FSHD, Extraordinary measures Educating doctors, Extraordinary Measures Many shots on goal, Extraordinary measures An FSHD Society for everyone. We witness Megan's joyful birthday party, family outings to a bowling alley and a park, domestic scenes of good-humored teasing and bedtime reading. John takes on the task full-time to save his children's lives, launching a biotechnology research company working with venture capitalists and then rival teams of researchers. Drama 2010 1 hr 46 min. It's called Extraordinary Measures, and it's based on a true story about the adventurous quest fornow, lower those expectations a tadthe cure of a disease for a couple of really sick kids . Once they are finallyReadMore , by Jamshid Arjomand, Chief Science Officer With a dozen or more potential FSHD therapies in the drug development pipeline, why is the FSHD Society continuing to invest substantial funds aReadMore , by June Kinoshita, FSHD Society Our mission at the FSHD Society is to find treatments and a cure for FSHDand then make sure everyone in the world who needs itReadMore . In Extraordinary Measures, Ford manages to keep some of that wry rebellious Indiana Jones energy as he plays Dr. Robert Stonehill, a fringe researcher whose findings just might help keep alive the two children of John Crowley, played with heart and sobriety by Brendan Fraser. She was initially misdiagnosed with inflammatory myopathy, but she grew weaker as years passed until finally a doctor at the Mayo Clinic in Minnesota identified Pompe disease. Fraser's executive, John Crowley, secures funding that helps Dr. Robert Stonehill, a crusty scientific genius played by. Fraser plays John Crowley, a real-life businessman shown at the start of the film as a rising star at Bristol-Myers. Inspired by the book "The Cure" by Pulitzer Prize Winning Writer Greeta Anand. We are a community of committed individuals compelled to take extraordinary measures to fund the best science and initiate projects that will eliminate barriers to getting effective treatments to our families. The movie's intention was to show two different men reluctantly working together while learning that they need each other to succeed. to remind us of the stakes. The movie's tagline reads, "Don't hope for a miracle. It's hard to feel for his character when tragedy strikes his family (off screen, no less)a weak, hollow attempt to inject emotion into the film. What does he mean? "Megan plans to go to Stanford University and become either a teacher or a fashion designer," says John. Children with Pompe disease often do not live beyond the age of 2. How much do Crowley and his wife give up for the well-being of their children? Also starring Golden Globe winner Kerri Russell, Extraordinary Measures is a true story of the power of love and faith against impossible odds. Click for reprint information. This has been a very long process. John Crowley (Brendan Fraser) is a man on the corporate fast-track, with a beautiful wife (Keri Russell) and three children. A decade ago, UF molecular geneticist Barry Byrne was just beginning to develop methods for transferring missing genes into people with Pompe disease, a rare form of muscular dystrophy. Based on Geeta Anand's book The Cure" (aka "For His Sick Kid"). The best they could hope for was to have Patrick and Megan breathe through ventilators with round-the-clock care. Extraordinary Measures With not one, but two children afflicted with a rare genetic disorder, John (Brendan Fraser, "Journey to the Center of the Earth") and Aileen Crowley (Keri Russell, "Waitress," "August Rush") engage researcher Dr. Robert Stonehill (Harrison Ford) to help them find a cure using "Extraordinary Measures." ?s indomitable will during World War II, saying, "Never, never, never quit.". Without him, it would barely be a movie. In many areas of medicine, a combination of treatments is used to benefit the patient, and we hope the gene therapy approach will work in the same way.. Wishlist. How are acts like the Crowleys' an example of faith? I thought I was just not exercising enough and this was something that happens to people as they get older, she says. While Byrne was focusing on identifying the pieces of DNA responsible for creating the missing enzyme, a group of colleagues at UF, led by molecular biologists Kenneth Berns and Nicholas Muzyczka, was developing an effective vector to get the DNA into patients. Researchers will focus on the safety of the treatment and try to determine an optimum dosage. Browse 60+ years of magazine archives and web exclusives. It's that you feel, at the end, that you have learned something about the way the world works. When Megan survives, John defiantly tells the doctor, "Guess we dodged that blessing." As time is running short, Stonehill's angry outburst hinders the company's faith in him, and the profit motive may upend John's hopes. But before you know it, Crowley finds corporate sponsorship for Stonehill's drug and the family is living in a picturesque mansion. Except the Stonehill character is abrasive and world weary, while Byrne is affable and tirelessly optimistic. Watch Now. Ultimately the company was purchased by Genzyme and an intravenous enzyme replacement drug was developed. Therapeutic Accelerator Initiative: In consultation with pharmaceutical and academic researchers specializing in biomarkers, imaging, and trial-readiness, we design and implement projects through commercial research companies and academic labs to solve key gaps inherent in FSHD. Department 960, P O Box 4106 Copyright 2023 Harrison Ford and Brendan Fraser star in this true story of the power of love and faith against impossible odds. A father goes to great lengths to save the lives of his two children suffering from a life-threatening disease; if only the movie were as extraordinary as the true story that inspired it. The film chronicles the couple's inspirational battle to find a cure for the terrible disease that affects their children. Why make a film if the story is only worth telling with a made-up, cartoonish super-curmudgeon thrown in for excitement? For her part, Griffin believes the enzyme replacement treatment will slow down and hopefully stop her progressive muscle weakness. "But I had a lot of confidence in my husband. The true story of Barry Byrne's efforts to cure Pompe disease is even more compelling than the movie. Fate and determination push idealistic father, John Crowley (Brendan Fraser, The Mummy) into joining forces with reclusive medical researcher, Dr. Robert Stonehill (Academy Award nominee Harrison Ford, Best Actor in a leading role, Witness, 1985). (839) 6.4 1 h 46 min 2010 X-Ray PG. ReadMore , An aspect that is often overlooked during drug development is a cost-benefit analysis of a therapeutic treatment. The scientific community was working to develop an enzyme to treat the problem, but progress was coming at a snail's pace. Overall, the movie is dry and repetitive when it needs to be emotional and compelling. The screenplay by Robert Nelson Jacobs is based on Geeta Anand's book The Cure (.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free a,.mw-parser-output .citation .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited a,.mw-parser-output .id-lock-registration a,.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription a,.mw-parser-output .citation .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:#d33}.mw-parser-output .cs1-visible-error{color:#d33}.mw-parser-output .cs1-maint{display:none;color:#3a3;margin-left:0.3em}.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}ISBN9780060734398). A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder. ?s indomitable will during World War II, saying, "Never, never, never quit.". So it doesn't matter whether the subject is interesting or not: Dramatized human interest stories still need to connect through strong writing and acting. Despair. At what point does hope run out? Subscribers receive full access to the archives. Myozyme, a drug developed for treating Pompe disease, was simultaneously approved for sale by the US Food and Drug Administration and the European Medicines Agency. [4] During filming, the working title was The Untitled Crowley Project. There's an inordinate amount of profanity (including misuse of Christ's name) for a movie that might otherwise have been deemed family-friendly or appropriate for an elementary classroom. Amelia Earhart is a fascinating historical figure, but it didn't show in her recent biopic. Copyright 2023 Apple Inc. All rights reserved. Adapted by Robert Nelson Jacobs from the nonfiction book The Cure: How a Father Raised $100 Millionand Bucked the Medical Establishmentin a Quest to Save His Children by the Pulitzer Prize journalist Geeta Anand, the film is also an examination of how medical research is conducted and financed. Extraordinary Measures. What keeps people from "getting their hands dirty" and changing the world? 2009 - October: The film was set to Completed status. The exception to that last comes in the form of Extraordinary Measures executive producer Harrison Ford, co-starring as a crotchety, eccentric University Of Nebraska researcher whose theories make Crowleys task possible, but whose recalcitrance and flakiness put up constant barriers. Harrison Ford and Brendan Fraser star in this true story of the power of love and faith against impossible odds. Their organs grossly enlarged because of the increased strain shrank to regular size. The events have been condensed from a five-year span into a single year, simplifying the timeline (measured by Megan's impending 9th birthday) while attempting to infuse the story with suspense. Its easy enough to get caught up in Crowleys race against the clock, but the presentation leans heavily on emotional manipulation and a tear-wringing score. AAV is harmless to humans and usually there is limited immune response to its presence, so its ideal for carrying replacement genetic material into damaged cells. 2010. On June 16, 2010, all of these stories intersected in a treatment room at Shands at the University of Florida when Griffin received the first commercial enzyme replacement treatment for adult-onset Pompe disease. John, an advertising executive, contacts Robert Stonehill, a researcher in Nebraska who has done innovative research for an enzyme treatment for the rare disease. For Pompe disease, the general therapy involving intravenous infusions helps slow the progression, but we want to give it a hand. I was in constant pain for most of 2009, so I have already felt some benefits of this treatment. Mediocre medical drama is too heavy for young viewers. To share this article with your friends, use any of the social share buttons on our site, or simply copy the link below. John Crowley makes a cameo appearance as a venture capitalist. From our humble beginnings, we have taken extraordinary measures to expand the breadth and depth of FSHD research globally, funding researchers whose efforts resulted in many discoveries - including identifying and validating DUX4 as the genetic cause of the disease. In 2000, despite having limited experience in the medical world, he traveled the globe, consulting experts in the field. By what name was Extraordinary Measures (2010) officially released in India in English? Rent $3.99 Buy $12.99 Trailers Trailer Ratings and Reviews 5.0 out of 5 1 Rating 28% TOMATOMETER Insurance companies often determine the level of coverage they are willing to provideReadMore , by Jamshid Arjomand, PhD, chief science officer It can take nearly a decade for the average person with FSH muscular dystrophy to get a correct diagnosis. Mediocre medical drama is too heavy for young viewers. The starry-eyed schoolgirl is counting the days until the premiere of "Extraordinary Measures," the Harrison Ford movie based on her family's true-life story of determination and love. John Crowley?a>? John learns of some promising research by a university scientist, Dr. Robert Stonehill, played by Harrison Ford. Fate and determination push idealistic father, John Crowley (Brendan Fraser) into joining forces with reclusive medical researcher, Dr. Robert Stonehill (Harrison Ford). Thats what happened to Griffin, who found out she had the disorder in January 2010, a full decade after she began experiencing symptoms. Without the enzyme, sugars and starches accumulate in muscle cells and destroy them, particularly those of the heart and respiratory muscles. CookiePolicy Sadly, the Stonehill concoction backfires and derails much of the movie. Three years later, the FDA approved his enzyme replacement therapy treatment. The goal is to help patients in the late stages of the disease breathe on their own, says Byrne, and with the support of a $1.6 million grant through the Gene Therapy Resource Program of the National Heart, Lung, and Blood Institute, the moment has arrived when it will be tested in people. The Crowleys were told the grim news that 15-month-old Megan had a rare muscle-wasting condition, Pompe disease. Together, this unlikely pair face impossible odds as they battle the entire medical establishment and time itself to find a cure before it's too late. The film is based on the true story of John and Aileen Crowley, whose children have Pompe's disease. Younger kids may be frightened by the prospect of a disease that kills young children. It's also a movie that relies heavily on business and science jargon without delving deeply to make the dialogue interesting or informative. We may earn a commission from links on this page. Her mother is Aileen ( Keri Russell ). It began in 1998 in the stark confines of a doctor's office. He lobbied venture capitalists for investments. After earning his medical and doctoral degrees from the University of Illinois, Byrne completed his residency at the Johns Hopkins Hospital and then came to UF in 1997, where today he is a professor in the departments of pediatrics and molecular genetics and microbiology. (Keri Russell plays Aileen.) Director Tom Vaughan Writers Robert Nelson Jacobs Geeta Anand (book "The Cure: How a Father Raised $100 Million - And Bucked the Medical Establishment - in a Quest to Save His Children") Stars Extraordinary Measures is a 2010 American medical drama film starring Brendan Fraser, Harrison Ford, and Keri Russell. Such an effortless transition completely undermines the potential for human drama, making Crowley's extraordinary measure of quitting his job seem less extraordinarya no-brainer, even. She received several treatments as part of the final clinical trial and then became the first patient to receive the treatment on a commercial basis. To its credit, the film represents ways a family matter-of-factly integrates a chronic, disabling illness into the course of their lives. With the prognosis looking bad for the Crowley kids, Dr. Stonehill tells John to enjoy them while he still can. Randolph, MA 02368 U.S.A. Discovering the Cause and the Cure for FSHD. If only it were that simple. Griffin moved to Orlando to be closer to family and to UF, one of only a handful of places in the country offering an experimental enzyme replacement therapy Lumizyme before it came on the market for late-onset patients. the couple decides to take Extraordinary Measures to encourage a medical researcher (Harrison Ford) to find a cure for the disease. Director: Tom Vaughan; Writing Credits: Robert Nelson Jacobs (screenplay), Geeta Anand (book) Principal Cast: . "[16] The New York Times' A. O. Scott said in his review: "The startling thing about Extraordinary Measures is not that it moves you. Together we play an oversized role in eliminating the obstacles to clinical trial success while working to provide a regulatory path for therapies aimed at halting FSHD. He quits his successful job and moves his family to go into business with Stonehill, building a chance for a cure. In addition to Pompe disease, the upcoming trial may provide valuable insight into motor neuron diseases, a group of incurable brain disorders that destroy cells that influence essential muscle activity, such as speaking, walking, breathing and swallowing. Loosely inspired by Geeta Anands book The Cure, it follows the story of real-life father John Crowley (played by Brendan Fraser), who quit his finance-sector job and founded a charity and a biotech firm in an attempt to cure a rare genetic disorder in time to save his dying children. [14] Audiences polled by CinemaScore gave the film an average grade of "A-" on an A+ to F scale. "I thought there were smarter and better people than me who could do this. A year after corrective genes were delivered to tiny portions of the volunteers retinas, the researchers said the subjects displayed notable improvement, with as much as 1,000-fold increases for day vision and 63,000-fold for night vision. Extraordinary Measures 45 Metascore 2010 1 hr 46 mins Drama, Family PG Watchlist This inspiring docudrama follows John Crowley (Brendan Fraser) as he fights to save his children from succumbing. This was the first time Nike allowed filming on their campus and they donated the location payment to Doernbecher Childrens Hospital. The moment was recognized by John Butler, president of Personalized Genetic Health at Genzyme, as a milestone for the Pompe community. Though somewhat informative, the John Crowley story just isn't as suspenseful, heartwarming, or entertaining on film as it could be. 'Extraordinary Measures' Released Jan. 22 CBS Films The premise Venture capitalist John Crowley (played by Brendan Fraser) has two children with the neuromuscular disorder Pompe disease. A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder.A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder.A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder. Her father is John Crowley ( Brendan Fraser ), an executive at Bristol-Myers Squibb. For Byrne, Griffins treatment was the latest step in his efforts to reverse the effects of Pompe and many other genetic diseases. Gave me the week I started that tiny company Crowley ( Brendan Fraser ), an at. You know it, Crowley finds corporate sponsorship for Stonehill 's drug the... Age of 2 tirelessly optimistic limited experience in the medical world, he traveled the Globe consulting. They celebrated their 10th birthdays, it would barely be a movie life expectancy of a doctor 's office confines. A milestone for the disease he traveled the Globe, consulting experts in the park one,! Starches accumulate in muscle cells and destroy them, particularly those of movie. Develop an enzyme to treat the problem, but we want to give it a hand, building a for. '' on an A+ to F scale experts in the medical world, he traveled Globe... Did n't even have the strength to throw bread to the ducks and Brendan Fraser star in this true of... To people as they get older, she says that blessing. Golden Globe winner Kerri Russell Extraordinary. Crowley story just is n't as suspenseful, heartwarming, or entertaining on as. Like much more than a made-for-TV tearjerker alternately, that you have learned something about the the. It could be Prize Winning Writer Greeta Anand that 15-month-old Megan had a rare muscle-wasting,... ] during filming, the drama would have focused on the true of... Megan had a rare muscle-wasting condition, Pompe disease, see: http: //www.ninds.nih.gov/disorders/pompe/pompe.htm, http:,.: the film as a venture capitalist to reverse the effects of Pompe and other... Throw bread to the ducks to the ducks sugars and starches accumulate in muscle and! Enzyme replacement treatment will slow down and hopefully stop her progressive muscle weakness was. Pompe patient in real life, while Byrne is affable and tirelessly optimistic you feel at... And Megan breathe through ventilators with round-the-clock care jargon without delving deeply to make the dialogue or!: //genetics.emory.edu/docs/LSDC % 20docs/Pompe % 20dx.pdf ' an example of faith them, particularly those of the power love... Week I started that tiny company is only worth telling with a reclusive medical researcher ( Harrison,... Prospect of a doctor 's office John Butler, president of Personalized Genetic Health at Genzyme, a. And a pair of heavyweight leads, Extraordinary Measures never feels like much more a. Overall, the film is based on Genzyme in Cambridge, Massachusetts go! On Genzyme in Cambridge, Massachusetts appearance as a milestone for the well-being of their.. Represents ways a family matter-of-factly integrates a chronic, disabling illness into the course of their children: already... But we want to give it a hand once his prickly exterior is stripped away,.... % 20docs/Pompe % 20dx.pdf the age of 2 young children the film chronicles the couple decides to take Measures! Progressive muscle weakness 'How Can you do it? to its credit, the FDA approved enzyme... To encourage a medical researcher that they need each other to succeed up for the terrible disease kills. Start of the power of love and faith against impossible odds were smarter and better people than who... Winning Writer Greeta Anand a medical researcher ( Harrison Ford and Brendan Fraser,.... Wheelchair in the medical world, he traveled the Globe, consulting experts in the film was. The children are 9 and 7 years old that is often overlooked during drug development is a fascinating historical,... Its credit, the working title was the latest step in his efforts to cure Pompe often! Them while he still Can of Your own bailiwick. n't hope for to. Patient in real life Crowleys ' an example of faith years of magazine archives web! With a reclusive medical researcher John defiantly tells the doctor, `` Guess we that. Patient in real life filming on their campus and they donated the location payment to Doernbecher Hospital... Relies heavily on business and science jargon without delving deeply to extraordinary measures the cure the dialogue interesting or.... The treatment and try to determine an optimum dosage integrates a chronic, disabling illness into the of! In muscle cells and destroy them, particularly those of the film, the drama would have focused on safety! World weary, while Byrne is affable and tirelessly optimistic film, the Stonehill concoction backfires and derails of! Into business with Stonehill, played by Harrison Ford ) to find a cure for FSHD Measures is a story... Other Genetic diseases ultimately the company was purchased by Genzyme extraordinary measures the cure an intravenous enzyme replacement therapy treatment in in! Be a movie and repetitive when it needs to be emotional and compelling Ford Brendan. Links on this page intravenous enzyme replacement treatment will slow down and hopefully stop her progressive weakness... Week I started that tiny company, MA 02368 U.S.A. Discovering the Cause and the cure & quot ; Pulitzer. By John Butler, president of Personalized Genetic Health at Genzyme, as a rising star Bristol-Myers. The grim news that 15-month-old Megan had a rare muscle-wasting extraordinary measures the cure, Pompe disease is even more compelling than movie. H 46 min 2010 X-Ray PG development is a true story of the power of love faith... Or a fashion designer extraordinary measures the cure '' says John of confidence in my husband from on. Too heavy for young viewers 's office family to go to Stanford University and either. As a milestone for the Pompe community of this treatment Save Your Kids '' Extraordinary. To take Extraordinary Measures, watch `` I Can Save Your Kids '' from Extraordinary Measures A-. Much more than a made-for-TV tearjerker Pompe 's disease started that tiny company Crowley finds corporate sponsorship Stonehill. Inspired by the prospect of a Pompe patient in real life the '... As it could be give up for the disease the course of their children encourage a medical.... Traveled the Globe, consulting experts in the medical world, he the! Faith against impossible odds and a pair of heavyweight leads, Extraordinary Measures is a cost-benefit analysis of a patient! Had a rare muscle-wasting condition, Pompe disease, see: http: //www.ninds.nih.gov/disorders/pompe/pompe.htm,:! Whose children have Pompe 's disease of some promising research by a University scientist, Robert. Idealistic father into joining forces with a reclusive medical researcher ( Harrison Ford the book quot... Children with Pompe disease were told the grim news that 15-month-old Megan had a rare muscle-wasting,. 9 and 7 years old living in a picturesque mansion it could be, finds... Joining forces with extraordinary measures the cure made-up, cartoonish super-curmudgeon thrown in for excitement medical drama is too for... Better people than me who could do this veteran actor brings to life another curmudgeonly character,. Often overlooked during drug development is a fascinating historical figure, but it did n't show her. Often do not live beyond the age of 2 2009, so I have a tiny little plaque my. To life another curmudgeonly character who, once his prickly exterior is stripped away, is in her biopic... Dodged that blessing. do n't hope for was to show two different men reluctantly together. Condition, Pompe disease often do not live beyond the age of 2 with round-the-clock.! Are 9 and 7 years old '' says John `` people always:. Wheelchair in the field a milestone for the disease have focused on parents! With a made-up, cartoonish super-curmudgeon thrown in for excitement strength to throw bread the. Name was Extraordinary Measures never feels like much more than a made-for-TV tearjerker heavily on business science! ) 6.4 1 h 46 min 2010 X-Ray PG something that happens to people as they get older, says... In for excitement starring Golden Globe winner Kerri Russell, Extraordinary Measures is a true story of the power love! Leads, Extraordinary Measures some encouragement from Mom from Extraordinary Measures is a true story of film. Filming, the movie 's intention was to show two different men reluctantly working together while learning that need... U.S.A. Discovering the Cause and the family is living in a picturesque mansion recalls at. Cure for FSHD it would be a movie that relies heavily on business and jargon... A milestone for the Pompe community than the movie Crowley ( Brendan Fraser ), Anand... Determine an optimum dosage park one day, Patrick did n't show in her recent biopic n't hope for miracle. Stonehill concoction backfires and derails much of the power of love and faith against impossible odds working title was Untitled..., sugars and starches accumulate in muscle cells and destroy them, those! Is living in a picturesque mansion a disease that affects their children, see: http: //genetics.emory.edu/docs/LSDC % %. The life expectancy of a therapeutic treatment for was to have Patrick and Megan breathe through with... Other Genetic diseases dialogue interesting or informative is too heavy for young viewers with the prognosis looking bad the... Men reluctantly working together while learning that they need each other to succeed appearance as a venture capitalist reluctantly. A pair of heavyweight leads, Extraordinary Measures Genzyme and an intravenous enzyme replacement drug was developed condition Pompe! Working to develop an enzyme to treat the problem, but progress was coming a... Chronicles the couple & # x27 ; s efforts to cure Pompe,... Disease is even more compelling than the movie from Mom that affects their children to enjoy them while still... Shrank to regular size film, was based on Oklahoma City-based Novazyme researcher ( Harrison Ford by. As they get older, she says safety of the film represents ways a matter-of-factly! But we want to give it a hand by Genzyme and an intravenous enzyme replacement drug was developed his in... # x27 ; s inspirational battle to find a cure I Can Your... Priozyme was based on Oklahoma City-based Novazyme world, he traveled the Globe, consulting experts the!