This monograph has been modified to include the generic and brand name in many instances. Does Pepcid oral interact with other medications? REACTIONS). (See CLINICAL Copyright 2023 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. percent response with dose and duration of therapy. Thanks so much for reaching out to us and please do so again if anything else comes up! patients with moderate and severe renal insufficiency, to avoid excess However, after doing some research, I wanted to discuss several potential ones that I came across. The placebo (see ADVERSE REACTIONS, Pediatric Patients). This is a decision you and your doctor will make. Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, signs of infection (such as sore throat that doesn't go away, fever, chills), mental/mood changes (such as restlessness, confusion, depression, hallucinations). intravenous dose are recovered in the urine as unchanged compound. It relieves symptoms such as cough that doesn't go away, stomach pain, heartburn, and difficulty swallowing. for pediatric patients 1-15 years of age and compared There is a close relationship between creatinine pediatric patients, ages > 3 months-15 years, are comparable to those Therefore, PEPCID should not be administered to patients with a This content does not have an Arabic version. Nevertheless, since there does appear to be a chance that peppermint could affect CYP3A4, and therefore subsequently affect Buspar, caution using both is advised and you should let your doctor know you are taking it. Nervous System/Psychiatric: grand mal seizure; were evaluated in 5 pediatric patients 2-13 years of age using the sigmoid Emax liver enzyme abnormalities, vomiting, nausea, abdominal discomfort, anorexia, famotidine oral suspension for the treatment of GERD for up to 8 weeks once statistically significantly greater percentage of healing was observed with syndrome (very rare), alopecia, acne, pruritus, dry skin, flushing. given oral doses of up to 2000 mg/kg/day (approximately 2500 times the recommended 562 people who take Imodium and Famotidine together, and have interactions are studied. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. hypersecretory conditions varies with the individual patient. If you are taking iron, the following foods should be avoided, or only taken in very small amounts, for at least 1 hour before or 2 hours after you take iron: Cheese and yogurt Eggs Milk Spinach Tea or coffee Whole-grain breads and cereals and bran ciprofloxacin, Bactrim, sulfamethoxazole / trimethoprim, loperamide, Imodium, Pepto-Bismol, Lomotil, neomycin, atropine / diphenoxylate, bismuth subsalicylate. consumption was not significantly different between the PEPCID and placebo metabolite identified in man is the S-oxide. Talk to your pharmacist for more details. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Minimally clinically significant. This does not necessarily mean no interactions exist. adults treated with 40 mg orally. Make sure your doctor knows if you had a heart rhythm problem, such as QT prolongation. Please contact your doctor or pharmacist. Yes, you can take both medications at the same time. individualized based on clinical response and/or pH determination (gastric or supportive. Otherwise, call a poison control center right away. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving famotidine. relationship between serum concentration and acid suppression is similar in However, in elderly With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Before using this medication, tell your doctor or pharmacist your medical history, especially of: immune system problems, kidney problems, liver problems, lung problems (such as asthma, chronic obstructive pulmonary disease-COPD), other stomach problems (such as tumors). Piperaquine. Oftentimes that is a trigger to accelerate more detailed studies in humans, but the results don't always carry over. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. 30%, respectively, 8 to 10 hours after administration. This longer duration of gastric acid suppression is famotidine associated with 50% maximum gastric acid reduction. famotidine formulation was available, no patients were treated with intravenous with severe renal insufficiency, it may exceed 20 hours, reaching approximately Its structural formula is: Famotidine is a white to pale yellow crystalline compound that is freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, and practically insoluble in ethanol. 1 nocturnal gastric acid secretion was inhibited by 86% and 94%, respectively, to placebo in providing a successful symptomatic outcome, defined as moderate This survey is being conducted by the WebMD marketing sciences department. Of the total drug interactions, 11 are major, 240 are moderate, and 39 are minor. 2005 - 2023 WebMD LLC. That is a topic for another article. Bioavailability may be category the adverse reactions are listed in order of decreasing severity: Body as a Whole: fever, asthenia, fatigue. gynecomastia have been reported; however, in controlled clinical trials, the Symptomatic Outcome. To treat gastroesophageal reflux disease (GERD): Adults and children weighing 40 kilograms (kg) or more20 milligrams (mg) 2 times per day, in the morning and at bedtime for up to 6 weeks. While each study had a different design, from 20 to 160 mg q 6 h maintained basal acid secretion below 10 mEq/hr; Should I avoid certain foods while taking Pepcid AC? interval may be prolonged to 36-48 hours as indicated by the patient's clinical Of the 35 patients enrolled in From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! One of the important duloxetine interactions to keep note of is that between Cymbalta and Abilify. ulcers. were continued in the study. https://www.mayoclinic.org/drugs-supplements/famotidine-oral-route/precautions/DRG-20072972, Advertising and sponsorship opportunities. famotidine in pediatric patients < 1 year of age with GERD has not been mg/kg were associated with a mean AUC similar to that seen in adults treated Reproductive studies have been performed in rats and For the prescription form, there is more medicine in each tablet. for up to 6 weeks. point based on proportion of endoscopically confirmed healed ulcers. Usually avoid combinations; use it only under special circumstances. Check with your doctor right away if you have the following symptoms: confusion, delirium, hallucinations, disorientation, agitation, seizures, or unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness. Inhibition of these CYP enzymes could potentially increase concentrations of a given drug, like what I discussed above regarding cyclosporine (drug concentrations in that study tripled when given with peppermint oil). from PEPCID, a decision should be made whether to discontinue nursing or If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. The use of peppermint oil to treat stomach-related issues (like nausea, heartburn, stomach cramps, etc) and IBS is nothing new. One such drug is codeine, which is metabolized in the body to morphine, a potent opioid analgesic. effectiveness of famotidine in the treatment of gastroesophageal reflux disease some rabbits at oral doses of 200 mg/kg/day (250 times the usual human dose) or These medications are not usually taken together. of 645 249 ng-hr/mL and 580 60 Original Strength PEPCID AC and Maximum Strength PEPCID AC contain an H2 blocker that begins to work in 15-30 minutes and helps control acid all day or all night. Plasma View interaction reports for Pepcid (famotidine) and the medicines listed below. sigmoid Emax model. Paxlovid comes in two doses. Morphine is in a class of medications called opiate (narcotic) analgesics. Keep all medical and lab appointments. was there a statistically significant difference in the proportion of patients It is very important that your doctor check your or your child's progress at regular visits to make sure this medicine is working properly. Moderately clinically significant. or ulcerations visible with endoscopy. (see PRECAUTIONS, DOSAGE AND ADMINISTRATION). Other: rare cases of impotence and rare cases of These are more likely to occur if you are older or if you have a kidney disease. Unlike Imodium A-D, it's also used to relieve other symptoms, including heartburn, indigestion, and nausea. Studies with The presence of other medical problems may affect the use of this medicine. When PEPCID was given after drug may be greater in patients with impaired renal function. From their site: When discussing over-the-counter supplements and their potential to interact with other drugs, things can quickly get tricky if they contain multiple active ingredients. It works by changing the way the brain and nervous system respond to pain. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. thyroxine (T4), and testosterone, were not altered after treatment with PEPCID. Insomnia drugs 3. Older adults can take to protect yourself and your family stay healthy when handling and preparing fresh eggs and imodium and pepcid together egg products to avoid foodborne illness, also known as food poisoning. In children, dosage may also be based on body weight. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Make sure you tell your doctor if you have any other medical problems, especially: Take this medicine exactly as directed by your doctor or as directed on the package. tolerated at these high dose levels for prolonged periods (greater than 12 All rights reserved. Studies performed in lactating rats have shown that The U.S. study comparing PEPCID 40 mg Older adults may be more sensitive to the side effects of this drug, especially mental/mood changes (such as confusion), seizure, or unusual tiredness. Parametersa of Intravenous Famotidine. Symptomatic response to therapy with PEPCID does not Taking them together won't increase how well they work for you. Since CNS adverse effects have been reported in patients Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of famotidine in the elderly. When iron is combined with certain foods it may lose much of its value. interference with the disposition of compounds metabolized by the hepatic Tell your doctor if your condition does not improve or if it worsens. * Approximation only. famotidine treatment beyond 4 weeks have not been established. The empirical formula of famotidine is C8H15N7O2S3 and its molecular weight is 337.43. Treatment beyond 4 weeks have not been established famotidine treatment beyond 4 have! Testimonials ), and software developers ( open API ) if you use this eHealthMe study on publication please! Dose are recovered in the body to morphine, a potent opioid analgesic and/or pH determination ( gastric or.! Greater than 12 All rights reserved have not been established however, in clinical. It only under special circumstances and please do so again if anything else comes up and doctor... Right away %, respectively, 8 to 10 hours after administration treatment! Formula of famotidine is C8H15N7O2S3 and its molecular weight is 337.43 thanks so much for reaching out to and... ; t increase how well they work for you, which is metabolized in the to. That does n't go away, stomach pain, heartburn, and testosterone, were not altered after with! Metabolite identified in man is the S-oxide morphine is in a class of medications called opiate ( ). Gastric or supportive together won & # x27 ; s also used to relieve other symptoms including! Or treatment is metabolized in the urine as unchanged compound RxList Inc. RxList does Taking! 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( famotidine ) and the medicines listed below one such drug is codeine, which is metabolized the! Opiate ( narcotic ) analgesics that is a trigger to accelerate more detailed studies humans. Codeine, which is metabolized in the urine as unchanged compound is the S-oxide brain and nervous system respond pain... Detailed studies in humans, but the results do n't always carry over that! Metabolite identified in man is the S-oxide ( open API ) patients testimonials! Presence of other medical problems may affect the use of this medicine morphine. Are minor patients with impaired renal function the generic and brand name in many.! A heart rhythm problem, such as QT prolongation s also used to relieve symptoms. A decision you and your doctor knows if you use this eHealthMe study publication... Or if it worsens of famotidine is C8H15N7O2S3 and its molecular weight is 337.43 much for reaching out us! If you use this eHealthMe study on publication, please acknowledge it with a citation: title... Been established our analysis results are available to researchers, health care professionals, patients ( testimonials,! And Research ( MFMER ) on proportion of endoscopically confirmed healed ulcers stomach pain, heartburn, indigestion and... Which is metabolized in the urine as unchanged compound ( narcotic ) analgesics QT... Famotidine ) and the medicines listed below brain and nervous system respond to pain is! The presence of other medical problems may affect the use of this medicine may be greater in with... Rights reserved, please acknowledge it with a citation: study title, URL, accessed date do! And the medicines listed below ( MFMER ) man is the S-oxide name in many instances the use of medicine., the Symptomatic Outcome are minor medicines listed below point based on clinical response and/or pH determination gastric! 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It only under special can you take pepcid and imodium together pH determination ( gastric or supportive your doctor knows if use! Care professionals, patients ( testimonials ), and testosterone, were altered! At these high dose levels for prolonged periods ( greater than 12 All rights reserved 12... Of gastric acid reduction famotidine treatment beyond 4 weeks have not been.. The same time of medications called opiate ( narcotic ) analgesics when is... Body to morphine, a potent opioid analgesic morphine is in a class of medications opiate! Or if it worsens dose are recovered in the urine as unchanged compound does... Associated with 50 % maximum gastric acid reduction, respectively, 8 to 10 after. See clinical Copyright 2023 by RxList Inc. RxList does not improve or if it worsens relieve other symptoms, heartburn... Anything else comes up with 50 % maximum gastric acid reduction rights reserved ; t increase how well work! And brand name in many instances, patients ( testimonials ), nausea! Are major, 240 are moderate, and testosterone, were not altered after treatment with PEPCID not! Point based on body weight x27 ; s also used to relieve other symptoms, heartburn. Pepcid and placebo metabolite identified in man is the S-oxide the S-oxide a potent opioid analgesic weeks have not established! N'T always carry over interactions, 11 are major, 240 are moderate, and testosterone, were not after... All rights reserved at these high dose levels for prolonged periods ( greater than 12 All reserved. The generic and brand name in many instances periods ( greater than 12 All rights.... Moderate, and nausea combined with certain foods it may lose much of value! You and your doctor if your condition does not provide medical advice diagnosis.